CA license #: LCS26742

EDUCATION

Undergraduate: University of Illinois, B.S., 2000 Champaign-Urbana, IL

Graduate: University of California, Berkeley M.S.W., 2003

TRAINING

Cognitive Behavior Therapy, 2002, SF Bay Area Center for Cognitive Therapy

Exposure Therapy, 2003, SF Bay Area Center for Cognitive Therapy

Dialectical Behavioral Therapy, 2003, John F Kennedy University DBT Program

Internal Family Systems Therapy, 2003-2005, IFS Institute

Mindfulness Based Cognitive Behavioral Therapy, 2009, MBCBT Training Program by Zindel Segal, PhD

Family Focused Therapy, 2010, FFT Training by David Miklowitz, PhD

Emotional Focused Therapy, 2015, 2020 Aikin Associates

Yoga Instructor Certification, 200-hr Yoga Teacher Training, 2016, Blissology Yoga

Cognitive Behavior Therapy, 2017, Beck Institute

Positive Psychology, 2017-2019, University of Pennsylvania by Martin Seligman, PhD

Acceptance and Commitment Therapy, 2018 - ongoing, Dr. Steven Hayes, PhD

Dialectical Behavioral Therapy, 2018- ongoing, Linehan Institute

Cognitive Behavior Therapy for Pediatric OCD, Mood, & Anxiety, 2019- 2020, Massachusetts General Hospital

Team Cognitive Behavior Therapy, 2019- ongoing, Feeling Good Institute

Family Based Treatment for Eating Disorders, 2021, Training Institute for Child and Adolescent Eating Disorders

MEMBERSHIPS

National Association of Social Workers

American Psychological Association

Anxiety and Depression Association of American

Team Cognitive Behavior Therapy

PEER REVIEWED MANUSCRIPTS (37 of 41)

Chang K, DelBello M, Garrett A, Kelley R, Howe M, Adler C, Welge J, Strakowski SM, Singh M. (2018). Neurofunctional Correlates of Response to Quetiapine in Adolescents with Bipolar Depression. J Child Adolesc Psychopharmacol, 28(6):379-386.

Chang K, Garrett A, Kelley R, Howe M, Sanders EM, Acquaye T, Bararpour L, Li S, Singh M, Jo B, Hallmayer J, Reiss A. (2017). Anomalous prefrontal-limbic activation and connectivity in youth at high-risk for bipolardisorder. J Affect Disord, 222:7-13.

Kim E, Garrett A, Boucher S, Park MH, Howe M, Sanders E, Kelley RG, Reiss AL, Chang KD, Singh MK. (2017) Inhibited Temperament and Hippocampal Volume in Offspring of Parents with Bipolar Disorder. J Child Adolesc Psychopharmacol. 2017 Apr;27(3):258-265.

Garrett AS, Miklowitz DJ, Howe ME, Singh MK, Acquaye TK, Hawkey CG, Glover GH, Reiss AL, Chang KD. (2015). Changes in brain activation following psychotherapy for youth with mood dysregulation at familial risk for bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry, 56:215-20.

Park MH, Sanders E, Howe M, Singh M, Hallmayer J, Kim E, Chang K. (2015) Association of Anxiety Symptoms in Offspring of Bipolar Parents with Serotonin Transporter-Linked Polymorphic Region (5-HTTLPR) Genotype. J Child Adolesc Psychopharmacol, 25(6):458-66

Kelley R, Chang KD, Garrett A, Alegría D, Thompson P, Howe M, L Reiss A. (2013). Deformations of amygdala morphology in familial pediatric bipolar disorder. Bipolar Disord.10

Singh MK, Jo B, Adleman NE, Howe M, Bararpour L, Kelley RG, Spielman D, Chang KD. (2013).Prospective neurochemical characterization of child offspring of parents with bipolar disorder.Psychiatry Res, 214(2):153-160.

Singh MK, Chang KD, Kelley RG, Cui X, Sherdell L, Howe ME, Gotlib IH, Reiss AL (January 2013). Reward Processing in Adolescents with Bipolar Disorder. J Am Acad Child Adolesc Psychiatry. 52(1):68-83.

Whitney J, Howe M, Shoemaker V, Li S, Marie Sanders E, Dijamco C, Acquaye T, Phillips J, Singh M, Chang K. (2013) Socio-emotional processing and functioning of youth at high risk for bipolar diosrder. J Affect Disord. 148 (1): 112-7

Garrett AS, Reiss AL, Howe ME, Kelley RG, Singh MK, Adleman NE, Karchemskiy A, Chang KD. (August 2012) Abnormal Amygdala and Prefrontal Cortex Activation to Facial Expression in Pediatric Bipolar Disorder. J Am Acad Child Adolesc Psychiatry. 51(8): 821-31.

J Roybal D Md, K Singh M Md, J Roybal V Md, E Cosgrove D Phd, Howe M, MSW, Kelley R Bs, Goraly NB Md, D Chang K Md. (2012) Biological Evidence for a Neurodevelopmental Model of Pediatric Bipolar Disorder. Isr J Psychiatry Relat Sci. 49(1):28-43.

Whitney J, Joormann J, Gotlib IH, Kelley RG, Acquaye T, Howe M, Chang KD, Singh MK. (March 2012) Information processing in adolescents with bipolar I disorder. J Child Psychol Psychiatry.

Singh MK, Chang KD, Chen MC, Kelley RG, Garrett A, Mitsunaga MM, Bararpour L, Howe M, Reiss AL, Gotlib IH. (September 2012) Volumetric reductions in the subgenual anterior cingulate cortex in adolescents with bipolar I disorder. Bipolar Disord. 14(6):585-96.

Karchemskiy A, Garrett A, Howe M, Adleman N, Simeonova DI, Alegria D, Reiss A, Chang K (December 2011) Amygdalar, hippocampal, and thalamic volumes in youth at high risk for development of bipolar disorder. Psychiatry Res. 194(3):319-25.

Liu IY, Howe M, Garrett A, Karchemskiy A, Kelley R, Alegria D, Reiss A, Chang K. (October 2011)Striatal volumes in pediatric bipolar patients with and without comorbid ADHD. Psychiatry Res.194(1):14-20.

Roybal DJ, Chang KD, Chen MC, Howe ME, Gotlib IH, Singh MK. (2011 Jun) Characterization and Factors Associated with Sleep Quality in Adolescents with Bipolar I Disorder. Child Psychiatry Hum Dev. 42(6):724-40.

Mitsunaga MM, Garrett A, Howe M, Karchemskiy A, Reiss A, Chang K. (April 2011) Increased subgenual cingulate cortext volume in pediatric bipolar disorder associated with mood stabilizer exposure. J Child Adolesc Psychopharmacol. 149-55.

Singh MK, Spielman D, Libby A, Adams E, Acquaye T, Howe M, Kelley R, Reiss A, Chang KD. (March 2011). Neurochemical deficits in the cerebellar vermis in child offspring of parents with bipolar disorder. Bipolar Disord 2011: 13: 189–197.

Miklowitz DJ, Chang KD, Taylor DO, Georg, EL, Singh MK, Schnec, CD, Dickinson LM, Howe, ME, Garber J. (2011) Early psychosocial intervention for youth at risk for bipolar I or II disorder: a one-year treatment development trial. Bipolar Disord. 13:67–75.

Singh MK, Spielman D, Libby A, Adams E, Acquaye T, Howe M, Kelley R, Reiss A, Chang KD. (January 2011) Neurochemical deficits in the cerebellar vermis in child offspring of parents with bipolar disorder. Bipolar Disorders. Volume 13, Issue 2, pgs 189-197.

Singh, MK, Spielman, D, Adleman, N, Alegria, D, Howe, M, Reiss, A, Chang, KD (2010) Brain glutamatergic characteristics of pediatric offspring of parents with bipolar disorder. Psychiatry Research: Neuroimaging. 182:165-171.

Chang, KD, Saxena, K, Howe, M, Simeonova, D (2010) Psychotropic Medication Exposure and Age at Onset of Bipolar Disorder in Offspring of Parents with Bipolar Disorder. J Child Adolesc Psychopharmacol. 20(1):25-32.

Singh, MK, Chang, KD, Mazaika, P, Garrett, A, Adleman, N, Kelley, R, Howe, M, Reiss, A. (2010)Neural Correlates of Response Inhibition in Pediatric Bipolar Disorder. J Child Adolesc Psychopharmacol. 20(1):15-24.

DelBello MP, Chang K, Welge JA, Adler CM, Rana M, Howe M, Bryan H, Vogel D, Sampang S, Delgado SV, Sorter M, Strakowski SM. (2009) A double-blind, placebo-controlled pilot study of quetiapine for depressed adolescents with bipolar disorder. Bipolar Disord. 11(5):483-93.

Wagner, KD, Redden, L, Kowatch, RA, Wilens, TE, Segal, S, Chang, KD, Howe, M, Wozniak, P, Vigna, NV, Abi-Saab, W, Saltarelli, M (2009) A double-blind, randomized, placebo-controlled trial of divalproex ER in the treatment of bipolar disorder in children and adolescents. J Am Acad Child Adolesc Psychiatry. 48(5):519-32.

Simeonova, DI, Jackson, V, Atalla, A, Karchemskiy, A, Howe, M, Adleman, N, Chang, KD (2009) Subcortical volumetric correlates of anxiety in familial pediatric bipolar disorder: A preliminary investigation. Psychiatry Res. 173(2):113-20

Barnea-Goraly, N, Chang, KD, Karchemskiy, A, Howe, M, Reiss, AL (2009). Limbic and corpus callosum aberrations in adolescents with bipolar disorder: A tract-based spatial statistics analysis. Biol Psychiatry. 66(3):238-44.

Chang, KD, Karchemskiy, A, Kelley, R, Howe, M, Garrett, A, Adleman, N, Reiss, AL (2009) Effect of divalproex on brain morphometry, chemistry, and function in youth at high-risk for bipolar disorder: a pilot study.J Child Adolesc Psychopharmacol 19:51-9.

DelBello MP, Chang K, Welge JA, Adler CM, Rana M, Howe M, Bryan H, Vogel D, Sampang S, Delgado SV, Sorter M, Strakowski SM. (2009) A double-blind, placebo-controlled pilot study of quetiapine for depressed adolescents with bipolar disorder. Bipolar Disord. 11(5):483-93.

Chang, K, Wagner, C, Garrett, A, Howe M. (2008), A preliminary functional magnetic resonance imaging study of prefrontal-amygdalar activation changes in adolescents with bipolar depression treated with lamotragine, Bipolar Disorders, 10(3):426-31.

Chang, K, Howe, M, Gallelli, K, Miklowitz, D. (2006), Prevention of pediatric bipolar disorder: Integration of neurobiological and psychosocial processes, ANN NY Acad Sci. Dec;1094:235-47.

Saxena, K, Howe, M, Iorgova, D, Steiner, H., Chang, KD (2005), Divalproex for the treatment of aggression in children and adolescents with subsyndromal bipolar disorder, J Child Adolesc Psychopharm. 16 (3):252-9.

Gallelli, K, Wagner, C, Karchemskiy, A, Howe, M, Spielman, D, Reiss, A, Chang, KD, (2005), N-acetylaspartate levels in bipolar offspring with and at high-risk for bipolar disorder, Bipolar Disorders, 7(6): 589-97.

Chang, KD, Saxena, K, Howe, M, (2005), An open-label study of lamotrigine adjunct or monotherapy for the treatment of adolescents with bipolar depression, Journal of the American Academy of Child and Adolescent Psychiatry, 45(3):298-304.

Baumer, F, Howe, M, Gallelli, K, Dimeonova, D, Hallmayer, J, Chang, KD, (2005), A pilot study of antidepressant-Induced mania in pediatric bipolar disorder: characteristics, risk factors, and the serotonin transporter gene, Biological Psychiatry, 60(9):1005-12.

Gallelli, K, Howe, M, Wagner, C, Spielman, D., Chang, KD (2005) Prefrontal neurometabolite changes following lamotrigine treatment in adolescents with bipolar depression, in review in Biological Psychiatry.

Chang, K, Wagner, C, Garret, Amy, Howe, M, Reiss, A, (2006) Prefrontal- Amygdalar Activation Changes in Adolescents with Bipolar Depression Treated with lamotrigine, in review in Journal of Bipolar Disorders.

BOOK CHAPTERS

Chang, KD, Howe, M, Simeonova, D. (2005), Advances in the Treatment of Bipolar Disorder in Children and Adolescents In: Advances in Treatments of Bipolar Disorders, Ketter, TA, Sachs, G, eds. Washington, D.C.:American Psychiatric Association Press, pp. 179-209.

Chang, KD, Howe M, Gallelli, K. (2005), Early Identification and Prevention of Early Onset Bipolar Disorder In: Prevention of Childhood Psychopathology.

ABSTRACTS (16 of over 50)

Alegria, D, Chang, K, *Howe, M, Hallmayer J., Association of Dopamine Gene Polymorphism with ADHD and Pediatric Bipolar Disorder. 55th Annual Meeting of the American Academy of Child and Adolescent Psychiatry, October 25-31, Chicago, Illinois.2008: Poster.

Chang, K, Nayar, D, *Howe, M., Atomoxetine as an Adjunctive Therapy in the Treatment of Comorbid ADHD in Children and Adolescents with Bipolar Disorder. 55th Annual Meeting of the American Academy of Child and Adolescent Psychiatry, October 25-31, Chicago, Illinois. 2008: Poster.

Howe,M, Chang, K, Environmental risk factors associated with Pediatric Bipolar Disorder. 158th Annual Meeting of the American Psychiatric Association, Washington, DC, May 01-10, 2008: Poster.

Howe, M, Yee, J, Karchemshy, A, Beenhakker, Chang, K.Longitudinal Study of Offspring at risk for Bipolar Disorder. 53rd Annual Meeting of the American Academy of Child and Adolescent Psychiatry, October 22-29, San Diego, California. 2006: Poster.

Simeonova, D, Attalla, A, Jackson, V, *Howe, M, Adleman, N, Karchemshy,Chang, K.Neuroanatomical Correlates of Anxiety in Familial Pediatric Bipolar Disorder. 53rd Annual Meeting of the American Academy of Child and Adolescent Psychiatry, October 22-29, San Diego, California. 2006: Poster.

Chang, K, *Howe, M, Karchemskiy, A, Wagner, C, Beenhakker, J,Hallmayer,J.Effect of BDNF Polymorphisms on Age at Onset and Hippocampal Volume in Pediatric Bipolar Disorder. 53rd Annual Meeting of the American Academy of Child and Adolescent Psychiatry, October 22-29, San Diego, California.2006: Poster.

Karchemskiy, A, Chang, M, Simeonova, D, *Howe, M, Garrett, A, Reiss, A,Chang, K. Decreased Amygdalar Volume in Familial Subsyndromal Bipolar Disorder. 53rd Annual Meeting of the American Academy of Child and Adolescent Psychiatry, October 22-29, San Diego, California. 2006: Poster.

Adleman, N, Karchemshiy, A, Howe, M, Garrett, A, Reiss, A, Chang, K. Mood and Gender Effects on Amygdala Activation in Pediatric BD. 53rd Annual Meeting of the American Academy of Child and Adolescent Psychiatry,October 22-29, San Diego, California. 2006: Poster.

Howe, M, Yee, J, Gallelli, K, Hallmayer, J, Chang, K. Investigation of Familial Pediatric Bipolar Disorder I, II, or NOS. 158th Annual Meeting of the American Psychiatric Association, Toronto, Canada, May 21-25, 2006: Poster.

Simeonova, DI, *Howe, M, Baumer, F, Strong, C, Ketter, T, Chang, KD. Creativity in Bipolar Offspring with and without Psychopathology. 52nd Annual Meeting of the American Academy of Child and Adolescent Psychiatry, October 18-23, Toronto, Canada: Poster.

Howe, M, Yee, Baumer, Hallmayer, J, and Chang, K. Gender Differences in Pediatric Mania. 157th Annual Meeting of the American Psychiatric Association, Atlanta, Georgia May 21-25. 2005:Poster.

Chang, K, *Howe, M, Saxena, K. Lamotrigine as Adjunctive or Monotherapy in Adolescent Bipolar Depression. 157th Annual Meeting of the American Psychiatric Association, Atlanta, Georgia May 21-25. 2005:Poster.

Howe, M, Yee, Baumer, Simeonoava, D, Hallmayer, J, and Chang, K. Age at Onset in Familial Bipolar Disorder. 51st Annual Meeting of the American Academy of Child and Adolescent Psychiatry, Washington, DC October 19-24, 2004:Poster.

Saxena, K, *Howe, M, Chang, K. Lamotrigine as Adjunctive or Monotherapy in Adolescent Bipolar Depression. 51st Annual Meeting of the American Academy of Child and Adolescent Psychiatry, Washington, DC October 19-24, 2004:Poster.

Hah, M, *Howe, M, Simeonova, D, Baumer, F, Yee, J, Chang, K. Pervasiveness and Severity of Depression in Bipolar Offspring. 51st Annual Meeting of the American Academy of Child and Adolescent Psychiatry, Washington, DC October 19-24, 2004:Poster.

Saxena K, Steiner H, *Howe M, and Chang, K. Divalproex Sodium reduces aggression in Bipolar Offspring with Psychopathology. 50thAnnual Meeting of the American Academy of Child and Adolescent Psychiatry, Miami, FL, October 22-27, 2003:Poster.